Endocrine Abstracts

Background: Polycystic ovary syndrome (PCOS) is a common disorder, yet not fully understood. Multiple hormonal and metabolic factors influence the pathophysiology of disease; resulting in various phenotypic characteristics among PCOS population. The luteinizing hormone/choriogonadotropin receptor (LHCGR, OMIM: 152790) is a G protein- coupled receptor mapped on chromosome 2p16.3; its coding region comprises 10 exons separated by 10 introns which transcript to protein w...

IntroductionPolycystic ovary syndrome (PCOS) is a common disorder that is not fully understood. Multiple hormonal and metabolic factors impact on disease pathophysiology resulting in various phenotypic characteristics among the PCOS population. Luteinizing hormone beta subunit (LHβ) (protein ID P01229) is mapped on (chr19p13.3) and consists of three exons. It is specific beta (β) subunit giving to LH from the anterior pituitary its specific fun...